However, when fed a plasmalogen supplement, the aged mice took a shorter, quicker route to the platform than those not given the supplement – suggesting improved cognitive function. After five days of training, young mice were able to remember the platform’s location, whereas aged mice took longer and swam further to reach the platform as they forgot its location. In this study, mice were trained to find a hidden platform in a pool of water (Morris water maze), and the image shows the paths they took to reach the platform. They found that mice that were fed the plasmalogen supplement had a higher number and quality of synapses – the connections between neurons – than the aged mice not given the supplements.Īged mice showed improved learning and memory when fed with plasmalogen supplements from Ascidiacea – also known as sea squirts. To find the reason for the improvement shown by plasmalogen-fed mice, the researchers took a closer look at changes happening within the brain. Older mice, on the other hand, take longer to locate the platform following the same amount of training.Īstonishingly, when fed with plasmalogens, aged mice perform more like young mice, finding the platform much quicker than the control group of aged mice that have not been given the supplement. Mice typically dislike swimming, so after five days of training, they remember where the platform is and swim directly to it as soon as they enter the pool. The effects of the plasmalogen supplement on learning and memory were evaluated by training mice to navigate a Morris water maze, which consists of a pool of water with a platform that acts as a resting place. The sea organisms Ascidiacea, also called sea squirts, contain substances called plasmalogens, which are vital to our body processes. This study is the first to show, in detail, how plasmalogens affect the aging brain. Additionally, aged mice fed with the plasmalogens grow new black hair that is thicker and glossier than aged mice not fed the supplement.” Professor Lei Fu, the corresponding author of the study, says: “Our research suggests that plasmalogens may not just stop cognitive decline, but may reverse cognitive impairments in the aging brain. They discovered that the supplements had a significant impact on the mice’s learning abilities and physical symptoms.
The researchers evaluated the effects of adding plasmalogens to the food of elderly mice to see whether increasing plasmalogen levels may prevent the effects of aging. This loss is also a characteristic of various neurodegenerative diseases, including Alzheimer’s and Parkinson’s. Plasmalogens are naturally found throughout our bodies, notably in the heart, brain, and immune cells, but the quantity in our bodies declines as we age.
These aquatic critters contain plasmalogens, which are essential to human body processes. Sea squirts may be eaten raw and can be found in recipes from Korea (where it is known as meongge, or 멍게) and Japan (hoya, or ホヤ). Sea squirts can be eaten raw and are found in dishes from Korea (where it is known as meongge, or 멍게) and Japan (hoya, or ホヤ).
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